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{"id":1086,"date":"2013-10-08T16:32:01","date_gmt":"2013-10-08T15:32:01","guid":{"rendered":"http:\/\/signalife.unice.fr\/?page_id=1086"},"modified":"2018-01-25T15:08:19","modified_gmt":"2018-01-25T14:08:19","slug":"genomics-and-bioinformatics","status":"publish","type":"page","link":"https:\/\/signalife.univ-cotedazur.fr\/?page_id=1086","title":{"rendered":"Genomics and bioinformatics"},"content":{"rendered":"
\nGENOMICS and BIOINFORMATICS<\/strong><\/span><\/h2>\n
![\"\"](\"http:\/\/signalife.unice.fr\/wp-content\/uploads\/2017\/12\/bernard-Mari.jpg\")
<\/a><\/p>\n![\"\"](\"http:\/\/signalife.unice.fr\/wp-content\/uploads\/2017\/12\/Christophari.png\")
<\/a><\/p>\n<\/p>\n
SIGNALIFE platform managers: Bernard Mari<\/strong> and
\nGael<\/strong> Cristofari<\/strong><\/em>
\nEmail:<\/em> mari@unice.fr<\/a> Phone:<\/em> 04.93.95.77.19
\nEmail:<\/em> Gael.Cristofari@unice.fr<\/a> Phone:<\/em> 04.93.37.70.87<\/p>\nThe two main Genomics platforms<\/strong> are located in Nice (IRCAN, Gael Cristofari) and Sophia-Antipolis (IPMC, Pascal Barbry), are complementary and have recently merged into the same structure, UCA GenomiX<\/strong> (certified IBiSA in 2017). They are open to local, especially SIGNALIFE members as well as external academic or non-academic members of the scientific community. Biostatistical and bioinformatics analyses are included in their offer. There is also a genotyping platform<\/strong>, equipped with a Sequenom in Nice (CAL, Gerard Milano). Additional Molecular Biology platforms<\/strong> have been developed at C3M and iBV, and notably include a Genome Editing facility<\/strong> (iBV) with the latest CRISPR \/ Cas9 technology for targeted genome modifications in various model organisms. All institutes are fully equipped with \u201ctraditional\u201d sequencing and several types of qPCR machines.<\/div>\n<\/p>\n
Functional Genomics Platform of Sophia-Antipolis<\/strong><\/span><\/h3>\n
![\"\"](\"http:\/\/signalife.unice.fr\/wp-content\/uploads\/2017\/12\/Barbry-235x300.jpg\")
<\/a><\/p>\n<\/p>\n
Head<\/em> Pascal Barbry<\/strong>
\nAddress<\/em>: Institut de Pharmacologie Mol\u00e9culaire et Cellulaire
\n![\"\"](\"http:\/\/signalife.unice.fr\/wp-content\/uploads\/2017\/12\/logo-genomics-300x105.jpg\")
<\/a>UMR 7275 CNRS \/ UNS
\n660, Route des Lucioles
\n06560 Sophia Antipolis<\/p>\nThe platform has been created in 1999, ISO9001 certified since 2006, and is a partner of the \u201cFrance-G\u00e9nomique\u201d infrastructure in biology and health (coordinator: P. Barby, IPMC; https:\/\/www.france-genomique.org). The lab is equipped with next-generation sequencing (NGS) Illumina NextSeq500, Ion Torrent PROTON and an Agilent array scanner and provides a wide range of expertise to academics and clinicians. Optimal protocols are proposed, notably for directional RNA and small RNA sequencing (miRNAs, piRNAs \u2026), total RNA depleted of ribosomal RNA, mRNA (polyA+ purifications), CHIP-SEQ and DNA resequencing. Recent developments have been focused on single-cell RNA-seq analyses (Fluidigm C1, Chromium Single Cell 10X Genomics) and long reads sequencing technologies (MinION, Oxford Nanopore Technology).<\/div>\n\u00a0![\"\"](\"http:\/\/signalife.unice.fr\/wp-content\/uploads\/2017\/12\/Illumina-Next.jpg\")
<\/a>\u00a0 \u00a0![\"\"](\"http:\/\/signalife.unice.fr\/wp-content\/uploads\/2017\/12\/Singjle-Cell-10x-300x176.jpg\")
<\/a><\/div>\nIllumina Next Seq 500\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Single-Cell 10X Genomics<\/strong><\/div>\n<\/p>\n
IRCAN Genomics Core Facility<\/strong><\/span><\/h3>\n
<\/a><\/em><\/p>\n
- Platforms
